supplements containing l theanine and l carnitine 200 mg of Zen L Carnitine 5000

TABLE 3 Summary of renoprotective approaches targeting autophagy/mitophagy in CP-induced AKI

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95% CI, 0.891.01

Reduce oxidative stress limit alcohol, processed foods, and chronic toxin exposure

In clinical studies, vitamin K2 reduces hepatic steatosis and lipid metabolism disorders by regulating liver lipid metabolism, inhibiting fat accumulation and inflammatory response (114)

Biochemical and omics biomarkers in cognition Classical CSF and plasma biomarkers A40 / A42 (important ratio in amyloid pathology) Total tau / p-tau181 / p-tau217 (tauopathic markers) Neurofilament light (NfL) : axonal degeneration marker GFAP : astrocytic activation BDNF and pro-BDNF : neurotrophic activity IL-6, TNF, IL-1 : neuroinflammation Transcriptomics and epigenomics Hippocampal RNA-seq after chronic administration of Semax or Selank often reveals a neurotrophic activation signature (BDNF, NT3, NGF, NR4A1-3) coupled with anti-inflammatory modulation (NF-B targets down)