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Although defective tight junctions potentially lead to compromised intestinal barrier and the development and progression of gastrointestinal (GI) diseases, no FDA-approved therapies that recover the epithelial tight junction barrier are currently available in clinical practice

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At 30 DAS, when approximately 60% of 35S::SLIM1 plants but less than 25% of slim1-cr and control plants have visibly bolted ( Figure 3A ), only one gene in the ROS/redox related set, COR78 (AT5G52310), appears to be regulated by SLIM1