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[PubMed: 12468113] 115

Supporting this, we also found that homocysteine was mildly positively correlated with age (r+0.20, P ~0.06), implying that as thalassemic children grow olderand many undergo splenectomy homocysteine tends to rise.Nitrotyrosine levels were unexpectedly lower in the postsplenectomy group (mean, 15.99.1 nmol/L) compared to the presplenectomy group (21.49.8 nmol/L, P =0.035)

10.1182/blood.v96.7.2606 59 PorterJ.CappelliniM

Both chemicals were dissolved in phosphate-buffered saline (PBS)

Limit high-fat and greasy foods (fried items, fatty meats, cream-based sauces), spicy foods, large portions, and carbonated beverages, especially during initial treatment and after dose increases, as these can worsen nausea, bloating, and gastrointestinal discomfort caused by delayed gastric emptying

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