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Recent studies suggest that novel drugs such as Ferrostatin-1 and Liproxstatin-1, by modulating iron-dependent cell death pathways, exert protective effects against ischemic stroke

"About 17 percent of Americans will be treated for depression at some point in their lives, but there are limited treatment options and about one-third of patients do not respond to these treatments."Lscher and his colleagues generated a mouse model for depression by introducing a mutation into a gene that codes for one of the subunits of a receptor for GABA -- the second most abundant chemical used by nerve cells in the brain to communicate

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Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling

TB-500: G-actin sequestration and actin-cytoskeleton remodelling in cell-migration assays