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Another very small study looked at IGF-1 supplements for children with Laron dwarfism, which is known to cause excessive body fat

Depression was measured using CES-D, which is not the gold standard clinical interview, while both chronic disease and CVD conditions were self-reported which could increase the risk of response bias

3 Division of Gastroenterology, Department of Medicine, Nanjing Medical University Nanjing First Hospital, Nanjing 210009, Peoples Republic of China

An imbalance in the intestinal barrier structure can flare up into an uncontrollable immune reaction in the intestinal microenvironment or allow the unrestrained growth of microbiota, which leads to various diseases, including intestinal inflammatory disorders, extra-intestinal autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, and metabolic disorders such as diabetes and obesity 4,5,6

Nobre, A

They are not approved drugs and are not intended to diagnose, treat, cure, or prevent any disease or medical condition