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Funding This work was supported by the National Key R&D Program (2016YFD0200305), the Young Elite Scientists Sponsorship Program by CAST (2018QNRC001), the Innovative Research Team Development Plan of the Ministry of Education of China (IRT_17R56) and the Fundamental Research Funds for the Central Universities (KYT201802)

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Approximately 60 % of patients are asymptomatic, with the disease often detected during routine blood work

The beauty of orthomolecular medicine is its broad applicability

HDAC6 deacetylates HSP90, enhancing its chaperone activity and promoting the stabilization and refolding of stress-damaged proteins (38)