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These findings may have broad implications for antibody engineering efforts aimed at enhancing the therapeutic activity of immunomodulatory antibodies

Turpeinen AM, Ylnen N, von Willebrand E, Basu S, Aro A

In addition, mtDNA alterations may contribute to the reverse Warburg effect, whereby cancer-associated fibroblasts (CAF) undergo aerobic glycolysis and secrete lactate or ketone bodies that are imported and oxidized by mtDNA-deficient tumor cells via residual mitochondrial pathways [215, 216]

J Mater Cycles Waste Manag

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Typically, there is an excessive production of androgens (androstenedione and testosterone male hormones) that cause common PCOS symptoms (excessive hair growth, acne) due to the hormonal imbalance