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mSystems 8 , e00532e00523 (2023)

Key reports on ME/CFS have shown abnormal metabolites produced which demonstrate disturbed Amino Acid metabolism, dysregulated lipid metabolism with possible glycolysis impairment, possible Pyruvate Dehydrogenase (PDH) impairment, Urea Cycle dysregulation and overall TCA cycle substrates provision deficiency and reliance these cells for alternate fuel sources

These findings together with observed difference in microglia between the expression of ferroptosis-related genes in A-related versus tau-related pathology [18] suggests that vulnerability to ferroptosis might be related to both increased A aggregation and tau hyperphosphorylation

Nosocomial infections caused by several bacteria cited in this review are difficult to eliminate because of multiple mechanisms that make them resistant to antibiotics specifically recommended for their treatment (78)

Eye lenses are optically clear structures behind the iris and in front of the vitreous body that focus light on the retina (8)