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The importance of Cat in the neoplastic scenarios has long been appreciated, as various studies have demonstrated that increased activity of this enzyme in tumour cells constitute a protection mechanism against cell death induced by reactive oxygen species (ROS), and that by inhibiting this enzyme, the neoplastic cells become once more vulnerable to this outcome [54], [55]

The COVID-19 pandemic, as highlighted by various epidemiological studies, exacerbated the global gap in PN management

Vitamin B12 plays a vital role in red blood cell production, nerve function, and cellular energy

Voltage gated calcium channels and chemical channels (i.e., glutamate) are well known calcium channels (Kumar et al., 2017)

Patients at low-risk for fracture should be considered for drug discontinuation after 3 to 5 years of use