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Neo-B12 Injection is also used to treat and prevent other forms of macrocytic anaemias caused by vitamin B12 deficiency, in which red blood cells that are larger than normal size result in a lack of haemoglobin

MedComm, 6 (10), Article e70401

In summary, ESM1 promotes angiogenesis via the regulation of angiogenic factors, and there is a reciprocal relationship between ESM1 and angiogenic factors, which form a positive feedback loop