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Large-scale, randomized controlled trials are critically needed to establish definitive efficacy for specific clinical indications and to compare these peptides with established therapies

A fold-change (FC) 1.2 or FC 0.83 in the experimental group compared with that in the control group was considered as up- or downregulation of phospho-specific proteins

A transparent explanation of evidence limitations and surgical risk priorities is more likely to preserve trust and compliance than confrontational dismissal

The proposed mechanism involves preventing GABA receptor downregulation, counteracting compensatory NMDA receptor sensitization, and stabilizing benzodiazepine receptor configuration

BPC-157 BPC-157 is a synthetic peptide that is researched for its potential to repair tissues

Liangshu Feng, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers