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p53 gene somatic mutations have been observed in both RA synovium and cultured FLSs

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The authors concluded that GHK and GHK-Cu increased epidermal cell stemness and keratinocyte proliferation, also increasing p63 and integrin expression [ 48 , 49 ]

To address these gaps, the objective of this systematic review is to evaluate the efficacy of currently investigated pharmacological and microbiota-targeted interventions in preclinical models of ASD [28]

Inhibiting pyroptosis in Mtb-infected macrophages through the PERK/eIF2/TXNIP/NLRP3/caspase-1/GSDMD axis reduces lung tissue damage and Mtb dissemination (Fu et al., 2021

The authors documented that the extracts lead to an increase in the level of GABA in the brain, especially in INH and PTZ models, which could be the possible mechanism of the extract (Alshabi et al., 2022)