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Description

One of the most frequently discussed concerns is related to skin whitening a desired outcome for many, but also a controversial one when pursued aggressively without clinical oversight

Nixon RA, Rubinsztein DC

However, these cells are highly sensitive to their environment, and elevated oxidative stress can physically trigger them to degranulate inappropriately

310, R1186R1192

10.1007/s00415-020-09723-5 296 LubomskiM.XuX.HolmesA

While early-stage localized melanoma is often curable through surgical resection (Tyrell et al., 2017), the prognosis for metastatic melanoma remains poor, with distant metastatic cases exhibiting a 5-year survival rate of less than one-third (Tao et al., 2025), underscoring the complexity of clinical management