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Both GLP-1(736)amide and GIP(142), active forms of GLP-1 and GIP, significantly reduced the atherosclerotic lesion area and plaque size, whereas GIP(342) and GLP-1(936)amide did not present the same effect

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The density of CD68 + macrophages is associated with poor prognosis, while CD38 is significantly expressed in the internal environment of human macrophages, which produces high levels of IL-6 and TNF-, and together with the expression of CD80, it causes more inflammation and helps to inhibit the tumor