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Start with just 0.5-1 mg total dose (about 0.25 mg per pound) and work up to a target range of 1-5 mg daily

Compared with the other two silica nanomaterials, solid silica nanoparticles upregulated the expression of LC3-II through ERK1/2 and AKT/mTOR signaling pathways, activated the autophagic flux of MSCs, and enhanced osteogenic differentiation potential

The combination is studied in connective-tissue, dermal, and angiogenesis models

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