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Indeed, HGF increases the proliferation of cerebellum granule cell precursors and this effect is reduced in a hypomorphic MET mutant (Grb2-binding incompetent) that leads to a smaller size of the cerebellum (Ieraci et al., 2002)

First, we validated that subcutaneous vascularity is increased in IMQ-treated mice and that versions of CSD decrease vascularity

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A key driver behind this cellular hyperexcitability is a specific ion channel called HCN2

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