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This might be a potential connection to GM and thyroid regulation suggested initially by the Harries (1923) more than hundred years back (Harries 1923)

the high GRK2 expression would sequestrate G and interfere with K + channels activation while in mature rats, homologous MOR desensitization would be due to receptor phosphorylation by this kinase (Llorente et al., 2012)

Salivary gland tissue chip screening identifies candidate radioprotective drugs

Deboever N, Feldman H, Eisenberg M, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG , Vaporciyan AA, Walsh GL, Hofstetter WL