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Data Availability Statement All data are contained within the main manuscript.

However, there was no positive effect on the IL-18 mRNA expression and TNF concentration with the treatment of nano-curcumin (Valizadeh et al., 2020

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[PubMed] [Google Scholar] 81.Cantarel B.L., Waubant E., Chehoud C., Kuczynski J., Desantis T.Z., Warrington J., Venkatesan A., Fraser C.M., Mowry E.M

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Animal experiments have shown that mice inoculated with lung cancer A549 cells treated with IGF-1 LR3 (0.2 mg/kg/d) showed a 2-fold increase in the number of lung metastatic nodules and a 30% reduction in survival time