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n indicates the number of biological replicates per condition

These tails are susceptible to suffer different chemical modifications in the lysine (K), serine (S), threonine (T) and arginine (R) amino acids (Smith and Denu, 2009

On the other hand, the DNMTi can enhance the function of cytotoxic T lymphocyte (CTL) by maintaining or upregulating the expression of IL-2, IFN-, and other anti-tumor cytokines through demethylation

The combined damage to the antioxidant system and the increased ROS production result in heightened oxidative stress, which in turn promotes PCa progression and metastasis by enhancing angiogenesis, altering the extracellular matrix, promoting inflammation, activating the UPR, and regulating miRNA expression

The authors also pointed out some markers ( i.e