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Cai C, Omwancha J, Hsieh CL, Shemshedini L

and a history of pancreatitis

& Doucet, E

Nevertheless, there are studies providing evidence for an influence of circulating UA on the pathology and behaviour of animal models of PD independent of any humanising effects on uricase activity

Indeed, the translocator protein (Tspo), a protein that binds to the voltage-dependent anion channel (VDAC) and interferes with redox balance 69,70,71 was upregulated after sUA+LPS stimulus in all macrophages analyzed, but in a more pronounced way in WT and Myd88 / cells