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OS: Conceptualization, Data curation, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

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In animal models, C2 supplementation promoted neuroplasticity, synthesis of neurotrophic factors, modulation of glutamatergic dysfunction, reversal of neuronal atrophy in regions like the hippocampus and amygdala, and improvement in depression-like behavioral symptoms [20, 30, 57, 58]

WHWT helped with human studies design and oversight

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Therefore, it is important to prevent inappropriate and/or overstimulation of the immune response in the liver to maintain physiological homeostasis