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Although DFO shows preclinical efficacy, its clinical translation remains limited, necessitating further evaluation of safety and effectiveness in stroke patients

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For example, when cardiomyocytes were incubated with the taurine transporter antagonist (guanidinoethane sulfonate-GES) or taurine transporter inhibitor (-alanine), mitochondrial oxidative stress increased and was accompanied by an accumulation of superoxide anions (O2), glutathione oxidation (GSSG), and inactivation of anti-oxidant enzymes such as aconitase (46,50)

Plant-based options like oats, edamame, and lentils also contribute, though typically in smaller amounts

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Methods of determining the conformation of epitopes include, but are not limited to, x-ray crystallography, two-dimensional nuclear magnetic resonance (2D-NMR) spectroscopy and site-directed spin labelling and electron paramagnetic resonance (EPR) spectroscopy