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Vitamin D3 RDA: 1,000 IU Vitamin D3 helps prevent macular degeneration and strengthens bones and teeth

The occurrence of ferroptosis is often accompanied by the dysregulation of the intracellular antioxidant system, particularly the loss of function of GPX4, which significantly reduces the cells ability to defend against lipid peroxidation ( Figure 1 )

Largely through the work of Dr

FIGURE 3 GO and KEGG analyses of the 59 aforementioned candidate targets indicated that the biological process (BP) terms of the target genes were mainly involved in the positive regulation of cell proliferation (GO:0008284), protein phosphorylation (GO:0006468), positive regulation of cell migration (GO:0030335), and negative regulation of apoptosis (GO:0043066)

Cell 61 , 210221 (2016)

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