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Lipophilicity with Purpose: These molecules walk a tightrope between being hydrophobic enough to cross membranes but not so greasy that they precipitate or bind non-specifically to proteins

Pilot PET study to assess the functional interplay between ABCB1 and ABCG2 at the human blood-brain barrier

TGs, which are considered as an inert lipid species, are recognized to be protective against toxic lipids

doi: 10.1016/j.bpj.2013.12.021 29 KraftML

negative or FRAA binding positive vs

This approach reduces fresh acid consumption, minimizes acidic effluent volume, and decreases washing water requirements by ~75%, thereby limiting acid-containing waste streams