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Furthermore, the analysis highlighted strong reductions in the Homeostasis Model Assessment of Insulin Resistance (HOMA-IR), confirming berberine's role as a potent insulin sensitizer

Transl Res (2021) 227:1529

Therefore, the results of some physical therapies should be used by caution and more well-conducted randomized controlled trials are needed to determine the level of evidence of some of these techniques

Santini F, Marzullo P, Rotondi M, Ceccarini G, Pagano L, Ippolito S et al (2014) Mechanisms in endocrinology: the crosstalk between thyroid gland and adipose tissue: signal integration in health and disease