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Thioredoxin and thioredoxin reductase in relation to reversible S-nitrosylation

Whenever RBCs are exposed to higher H 2 O 2 levels, CAT becomes essential for its rapid removal since this enzyme has a high turnover rate, unlike GPx and Prx2 that become less efficient (or even inactive), due to their slow GSH reductase and Trx recycling systems, respectively [59, 60, 73]