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[DOI] [PubMed] [Google Scholar] Bruchhausen S, Zahn S, Valk E, Knop J, Becker D

This means that ferroptosis can induce other kinds of cell death, and/or it plays a minor effect in cell death, or we use inhibitors after the reversible point and once this threshold is exceeded, ferroptosis will be irreversible Recently, we also found that ferroptosis is vital for tumor immunity such as macrophage phagocytosis (71) and T cell killing (115) but the crosstalk between ferroptosis and the glioma immunosuppressive microenvironment is not clear

Gamma-glutamyl cycle and enzyme deficiencies (highlighted in red) related to different diseases (highlighted in blue)

When the degradation of GS 2 Hg to Hg(SCyGly) 2 was inhibited by treatment with a specific inhibitor of GGT, this did not decrease Hg uptake, but decreased its cytotoxicity [98]