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Embodiment 18: the apparent metabolism relevant with the tumor obstacle changes the evaluation of agent Utilize the apparent metabolism transformation of the candidate agent of varying level to handle one group of Skin Cell system, it is by control cells system (for example, horn cell and melanocytic primary culture) and cancerous cell line (for example, SK-MEL-28, non-metastatic skin melanoma

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Ng F, Berk M, Dean O, Bush AI (2008) Oxidative stress in psychiatric disorders: evidence base and therapeutic implications