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Conversely, the authors also found that copper deficiency decreases the formation of autophagy-initiating phagophores, which contain important ULK1/2 downstream targets ( Figure 1 )

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Liu T, Hu L, Lu B, Bo Y, Liao Y, Zhan J, et al

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Dysbiosis has been associated with reduced therapeutic efficacy, while microbial restoration strategies, such as faecal microbiota transplantation (FMT) and probiotic supplementation, have been shown to enhance immunotherapy outcomes [21]

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