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[DOI] [PubMed] [Google Scholar] 8.Stabler S.P., Allen R.H., Savage D.G., Lindenbaum J

These authors showed that a ligand-free ligand binding domain (LBD) of PPAR is significantly more flexible than the rest of the LBD, indicating that this binding pocket is intrinsically disordered in order to accommodate different ligands (Hamuro et al., 2006)

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This approach maintains more consistent peptide levels throughout the day

The synthetic analogs of natural peptide ligands are of major interest for PDCs as they possess high target affinity and specificity, fast internalization rates, and low immunogenicity

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