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Novel clinically relevant proteasome inhibitors and HDAC inhibitors

The slices were placed in artificial cerebrospinal fluid at 37 C (aCSF: 125 mM NaCl, 2.5 mM KCl, 1.25 mM NaHPO 4, 25 mM NaHCO 3 , 25 mM D-Glucose, 2 mM CaCl 2 and 1 mM MgCl 2 , bubbled with carbogen for 30 min)

Kidney function decline is a major driver of aging-related morbidity

In this article we have highlighted many different astrocyte-associated molecules that are emerging as potential therapeutic targets in different disorder contexts

Natural products: potential treatments for cisplatin-induced nephrotoxicity

Chemokines in target cell tissues can also induce directed cell migration, initiate signal pathways, and monitor cytoskeletal rearrangment and adhesion (91)