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The discontinuation rate in clinical trials ranged between 20% and 50% within the first year, with GI intolerance being the primary reason

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[DOI] [Google Scholar] 33.Keremi B., Lohinai Z., Komora P., Duhaj S., Borsi K., Jobbagy-Ovari G., Kallo K., Szekely A.D., Fazekas A., Dobo-Nagy C., et al

Among the properties of biomolecules which have been measured by these mass spectrometric techniques are the gas-phase basicity of amino acids [102,103,104,105] and of DNA nucleotides [103,106,107,108] and the reduction potential of the disulfide-thiol pairs of amino acids and peptides of the soluble thiolome [101]