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The field is dynamically shifting, it truly is

The result is preserved intracellular pools of nicotinamide ( NAD+ salvage substrate) and SAM ( methyl-donor pool)

It has an improved ability to inhibit the enzymatic activity of NNMT and drastically reduces the formation of MNAM

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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Stromsdorfer KL, Yamaguchi S, Yoon MJ, Moseley AC, Franczyk MP, Kelly SC, Qi N, Imai S, Yoshino J

This is a conversation to have with your clinician rather than a fixed schedule to follow on your own