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FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway PMC foxo4 dri senolytic mouse 2023 2024 Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging: Cell Peptide targeting senescent cells restores Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine Peptide targeting senescent cells restores stamina, fur, and kidney function in old mice EurekAlert! CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS
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