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J Neurol Sci (2017) 376:423

Although most infected individuals experience mild or asymptomatic disease, approximately 14% develop severe illness and about 5% progress to critical conditions, among whom mortality may reach up to 50%

The N -selenoethyl arm of the target amino acid, Se -protected with a PMB group, was inserted by reductive amination reaction 50

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Ann Clin Biochem 41:157159 Stabler SP, Marcell PD, Podell ER, Allen RH, Savage DG, Lindenbaum J (1988) Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography mass spectrometry