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He graduated from Harvard Medical School in 1945, interned at the University of Chicago, and worked for several years in the Veterans Administration

10.3390/ijms160612092 73 LinY.CaiJ.HuangD.ZhouB.LuoZ.YuS.et al (2022)

Although many of these are present in healthy neurons, several events can lead to their overproduction which, ultimately damages cellular components leading to neuronal dysfunction and increased severity and area of affliction in a time dependent manner 2,3,4