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The authors drew conclusions indicating that Epitalon influences AChE, BuChE, and APP metabolism, positioning it as a possible candidate for the treatment of cholinergic deficiency diseases and cognitive disorders associated with amyloid metabolism [45]

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Through in vitro neural and oligodendrocyte progenitor cell (OPC) cultures, ex vivo cerebellar explants, and in vivo mouse models of PBI and MS, we identify FDA-approved leucovorin and dyclonine as promising candidates

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