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While the immune system can recognize and destroy cancer cells, tumors often develop mechanisms to evade immune surveillance [121]

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Additionally, serum zinc concentrations decline with age, with a more significant reduction observed in patients with Alzheimer's disease (AD) than in healthy individuals of similar age (Brewer, 2012[52])

53 It was also postulated that pro-inflammatory cytokines in macrophages were produced when toll-like receptors stimulated XBP1s via NOX2 signaling

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The mechanism of -Catenin mutation-related HCC is induced by -Catenin -GS-mTORC1 axis