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These findings suggest that despite bearing a reactive electrophile, C1-27 did not bind to cellular proteins indiscriminately but appeared to exhibit certain degree of selectivity in target binding

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Because of their control over oxidative stress-related ageing and apoptosis, mitochondria are considered a dominant source of ROS [14]

Ionization (or deionization) within a proteins structure can have significant effect on the overall conformation of the protein and, since structure is related to function, a major impact on the activity of a protein

Cancer 6, 583 (2015), Application(s): Aggresome detection by fluorescence microscopy in peritoneal macrophages, Abstract Full Text Decreased proteasomal function accelerates cigarette smoke-induced pulmonary emphysema in mice: Y

Vitamin B3 is crucial for the synthesis of glutathione in the lens, where glutathione acts as a primary antioxidant against oxidative damage