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However, researchers emphasized that larger and more comprehensive studies are still needed before definitive conclusions can be made

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The plasma concentration of total dabigatran was determined via by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) after oral administration of the test preparation or reference preparation to the subjects [18, 19]

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Mataranyika PA, Kibuule D, Kalemeera F, Kaurac H

Also, most mechanistic, epigenetic, endocrine, and microbiome studies to date have been conducted in high-income settings, while studies from LMICs are more observational or epidemiologic, limiting the generalizability of findings