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In: Hoffman R, Benz EJ, Silberstein LE, et al, eds

Its primary research focus involves elevating intracellular NAD+ levels, which is crucial for cellular energy metabolism, DNA repair, and overall cellular function

Over time, if left untreated, the deficiency can make you prone to alarming consequences such as anemia, nerve damage, cognitive impairment, and even psychiatric disorders

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On a cellular level, B12 serves as an essential cofactor for two key enzymatic reactions involving methionine synthase and methylmalonyl-CoA mutase

Briefly, the antibodies were cross-linked to Protein A Sepharose beads with dimethyl pimelimidate (Sigma) and lysates were incubated overnight with each antibody