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The mechanism is only partially understood but involves reduction of gene and protein expressions of fibrotic and inflammatory markers such as TGF-, TNF-, IL-2, MMP-9, vimentin and enhancement of antioxidant ability by increment of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and by preservation of mitochondrial function [215]

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Copper peptides used in skincare are generally regulated as cosmetic ingredients rather than as medicines, and no GHK-Cu product is FDA-approved to treat, cure, or prevent any disease