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For this reason, sulfate assimilation, which is highly regulated by the demand for reduced sulfur, is also notably dependent on the nitrogen status ( 2 S), cysteine, S-adenosyl-methionine (SAM) and glutathione, exert inhibitory effects at the post-translational level (Wirtz et al., 2010)

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1 Introduction The glutathione peroxidase family (GPX) is a family of antioxidant enzymes that are an essential class of selenoenzymes in mammals ( 2 O 2 or organic hydroperoxides to water or corresponding alcohols, thereby mitigating their toxicity ( In mammals, GPX works with superoxide dismutase and catalase to form an enzymatic antioxidant system that reduces reactive oxygen species (ROS) and limits their toxicity

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These effects are partly mediated through the activation of Sirts and improved mitochondrial function