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(G2019S) LRRK2 causes early-phase dysfunction of SNpc dopaminergic neurons and impairment of corticostriatal long-term depression in the PD transgenic mouse

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It is naturally found in high concentrations in the liver, and plays a critical role in detoxification processes there by binding to toxins and facilitating their removal from the body

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For most recreational exercisers, this is imperceptible