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As anticipated, our findings show that most natural flavonoids activate antioxidant systems, primarily by modulating the Nrf2/GPX4 axis, with some also affecting ferritin or reducing iron accumulation in neurons, thereby further promoting the inhibition of ferroptosis

Sophie Brenner, Corinne Lecuivre and Michael Eppe (students from the Institut Paul Lambin, Brussels, Belgium) for technical help

Interestingly, individuals with higher adherence to the Mediterranean diet had lower levels of Oscillobacter and more favorable lactate dehydrogenase concentrations [140]

It is used to dissolve or dilute medication and ensure proper consistency for injection

Additionally, PFs can affect the gutliver axis through the activation of the FXR/RXRPXR signaling pathway, thereby increasing the capacity of the liver to detoxify foreign substances and increasing the ability of the liver to remove harmful toxins from the body via bile acids, thus illustrating the systemic detoxification effect initiated in the gut (Zhang et al

"Clinical Pharmacokinetics and Pharmacodynamics of Warfarin Understanding the Dose-Effect Relationship"