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They tend to have reduced bone repair and increased fracture risk, presenting a treatment challenge

& Strazzabosco, M

Discontinue use if skin becomes irritated

Reducing exposure to sources of immediate gratification while increasing opportunities for effortful, meaningful activities creates conditions that support dopamine system recovery

Important contraindications include personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), history of pancreatitis, severe gastrointestinal disease including gastroparesis, and pregnancy or planned pregnancy (these medications should be discontinued at least 2 months before a planned pregnancy)

Yang, M., et al., Clockophagy is a novel selective autophagy process favoring ferroptosis