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Inherited Disorders of Folate Transport and Metabolism Several inherited disorders of folate metabolism and transport have been described [4] (see Table 2 ), for example: MTHFR deficiency, MTR deficiency (either caused by mutations in MTR gene or MTRR gene), ecerebral folate deficiency ( CFD ) (caused by FOLR1 mutation), hereditary folate malabsorption, and glutamate formiminotransferase ( FTCD ) deficiency

Abstract Canities (or hair greying) is an age-linked loss of the natural pigment called melanin from hair

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This lesion is not observed in humans

They found that some of the hairs began as gray or white and reverted back to their original pigmented color

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