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the results from this phase 3b clinical trial may not be generalizable to the broader population of hospitalized patients with schizophrenia who are initiating LAIs 1,3 The approval of ARISTADA was based on the phase 3, 12-week, pivotal study that compared the 441 mg and 882 mg monthly doses to placebo at Day 85

There were no statistically significant differences in age between the groups initially diagnosed with or without VCD, as indicated in Table 1

Discussion Recent research has significantly advanced our understanding of sarcopenia, an age-related condition marked by muscle deterioration

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It also clearly demonstrates that the role of RABGAP1 in APP trafficking is dependent on its GAP activity, suggesting that it mediates this effect through RAB protein inactivation