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Individuals with obesity demonstrate elevated levels of ROS and compromised antioxidant defenses, with the imbalance between oxidants and antioxidants closely correlated with obesity parameters, including BMI (149, 180183)

One mouse study reported no increase in mean lifespan

Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway

Furthermore, diverse chemical treatments have been identified to limit ROS accumulation by affecting either their production or processing

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