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Biochem Biophys Res Commun 515(3):462467 Cheng Y, Tian D-Y, Wang Y-J (2020) Peripheral clearance of brain-derived A in Alzheimers disease: pathophysiology and therapeutic perspectives

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Acknowledgements The financial support was provided by Irish Government, the Atlantic Philanthropies and Irish Life plc

The intervertebral disc can be affected primarily by damaging or loss of organ tissue or, secondarily, through metabolic, immunological or biomechanical changes, such as segmental instability with subsequent damage the disc organ

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